Best Ergonomic Mouse For Wrist Pain With Detailed Reviews

It is time to say goodbye to wrist pain! The reputable brands in the market offer a wide range of ergonomic mice to offer comfort and support to the wrist and prevent any sort of injury for daily computer work.

Prolonged use of regular mouse has been identified as one of the causes for carpal tunnel, Gout, and other issues. Are you having one of those issues? So, switching to the best ergonomic mouse for wrist pain can significantly reduce the chance of developing such problems.

Regular mouse does not have any orientation and does not offer an ergonomic posture that can provide comfort to those who work for extended periods of time. However, here you can find the most affordable, durable, and portable ergonomic mouse with a little research that is worth spending on.

Are you ready to get your hands on the best computer mouse models? Let’s move on to our well-researched list.

At a Glance:

What Key Components Should be in An Ergonomic Mouse?

  • An ergonomic mouse should have a comfortable grip to work with it without resistance or discomfort for long hours.
  • The buttons on the mouse should be soft and smooth so that they don’t get pressed unintentionally while working.
  • It should also have an adjustable DPI to enable the users to change the mouse sensitivity settings.
  • A back and forward mouse button should be present on either side of it to facilitate quick browsing and avoid unnecessary scrolling.
  • Try to look for a wireless mouse that enables you to work from a distance without any wire restrictions.

Perixx PERIMICE-713 Wireless Ergonomic Vertical Mouse

Best Pick
Connectivity TechnologyRadioFrequency
Recommended Uses For ProductOffice
Compatible DevicesComputer
Special FeaturesErgonomic design

The Perixx PERIMICE-713 Wireless Ergonomic Vertical Mouse is the perfect solution for this problem since it offers your hands an ergonomic grip while also reducing wrist strain through its vertical orientation. It comes with three adjustable levels of DPI sensitivity, so you have more control over the speed at which you move the mouse pointer on your screen.

This wireless 2.4GHz ergonomic vertical mouse provides up to 10 meters range operation distance and consumes minimal power, making it a good investment for home users and businesses where multiple employees work together in one computer set up.

Moreover, the nano USB receiver is located conveniently at the bottom of the mouse, and it is compatible with Windows 7, 8, and 10.

Product Highlights:

  • It is designed for right-handed users that promotes a more natural position while using the mouse for long-lasting comfort.
  • Computer mouse sensitivity can be changed with the DPI control button as it has adjustable 3 DPI levels of the 800/ 1200 (default)/ 1600.

Final Verdict:

So if you’re looking for a wireless vertical ergonomic mouse that offers a comfy position and incredible comfort to your wrist while working on your computer, then be sure to give priority to Perixx PERIMICE-713 Wireless, as it is equipped with all the necessary features for an effective user experience.


  • There is no need for a mouse pad
  • Wireless and portable
  • Power-saving function for battery preservation
  • Works on multiple platforms


  • The button placement is a bit weird
  • Charging time is a bit long

LEKVEY Wireless Vertical Ergonomic Mouse

Staff Pick
Connectivity TechnologyWireless, USB
Recommended Uses For ProductOffice, Gaming
Compatible DevicesLaptop, Personal Computer
Motion Detection TechnologyOptical

Lekvey presents the best vertical ergonomic mouse, which is wireless. It fits the palm and is suitable for medium hands. The DPI level can be adjusted as per user comfort. It has a built-in long battery life and is rechargeable. So this eliminates the need to buy batteries regularly, which will save you money in the long run.

Moreover, it has a nano receiver, so connecting is no inconvenience. With the page forward button, browsing pages is easy if you are surfing. Also, this mouse is compatible with Windows 2000/XP/Vista/7/8/10 and Linux. Overall, it’s a good investment at its rate.

Product Highlights:

  • Mouse adjusts sensitivity to your needs with 800/1200/1600 DPI adjustable levels.
  • High capacity rechargeable battery with a USB charging cable included with your purchase.

Final Verdict:

The best ergonomic mouse for wrist pain would be the one that corrects our poor posture. If you face wrist pain or carpal tunnel problems, then the Lekvey Vertical mouse is for you, and it will facilitate your health too. Moreover, the DPI level can be adjusted to suit varying preferences & wireless features, making it convenient, so it’s a great investment.


  • Plug and play mouse
  • High-capacity rechargeable battery
  • Precise tracking
  • Maintains neutral position


  • Receiver storage is in an awkward location
  • Not compatible with Mac OS, Apple Products

Logitech MX Ergo – Wireless Trackball Mouse

Budget Pick
Connectivity TechnologyWireless, Bluetooth, USB
Compatible DevicesPC
SetsLogitech MX ERGO
Special FeaturesWithout alcohol

Are you looking for the best wireless thumb-controlled trackball mouse for wrist pain? If so, then it’s time to try out the Logitech MX Ergo Wireless Trackball Mouse. It has a symmetrical trackball that is designed so you can comfortably perform any office task while helping provide a more relaxed wrist position like an apple magic mouse.

Of course, this device has some additional features that distinguish it from other wireless trackballs currently on the market.

Its cross-computer control feature allows you to move around between two computers by simply pressing one button. Its minimal and maximal value is 512-2048 DPI. It can also be paired more easily with Bluetooth technology, and its rechargeable battery lets you use the trackball for up to 70 days on a single charge.

Product Highlights:

  • The unique adjustable hinge allows you to customize the trackball angle from 0 to 20 degrees for a more natural, comfortable hand position.
  • Use with up to 3 Windows or Mac computers via Logitech unifying receiver or Bluetooth smart wireless technology.

Final Verdict:

Logitech MX Ergonomic Horizontal mouse for wrist pain is one of the best trackball mice that you can buy. It provides a more relaxed wrist position and has excellent connection features to meet all your needs. By just turning the angle of this ball, you will be able to reduce the risk of carpal tunnel syndrome and other kinds of strain that result from repeated mouse movements.


  • Ergonomic sculpted design.
  • Dual connectivity.
  • Low power consumption.
  • Precision scroll wheel tilt.


  • A bit expensive comparatively.
  • A bit heavy.

Anker 2.4G Wireless Ergonomic Vertical Optical Mouse

connectivity technologyUsb, Wireless
Compatible devicesWindows 10 / 8 / 7 / Vista / XP / 2000 Linux Mac OS X
motion detection technologyOptical

Now get rid of your old uncomfortable mouse with the new Anker 2.4G Wireless ergonomic vertical mouse. It is best for people with wrist pain because it offers neutral or ‘handshake’ positioning.

The optical tracking technology provides excellent performance on a wide range of surfaces like wood, glass, or marble table-tops without any hassle. The 800, 1200, and 1600 DPI resolution gives a high level of precision. 

If you want to make use of another mouse from now on, you should know that it is supported by Windows XP, Vista, 7, 8, and Mac, and it requires two AAA batteries that last for a long time. You can easily purchase this product from Amazon and get an 18-month hassle-free replacement warranty.

Product Highlights:

  • The product weight is 3.4 oz, so it is easy to carry and use.
  • The added next/previous buttons enable to move between webpages forward or backward with ease.

Final Verdict:

Anker 2.4G Wireless Vertical Ergonomic Optical Mouse is great for people who suffer from wrist aches. When it comes to sensitivity, this mouse offers three options so that you can find what works best on any surface. The sleek design of this mouse makes it easy to take with you on the go.


  • This ergonomic model reduces wrist strain
  • Optical tracking works on a wide range of surfaces
  • Buttons provide convenience for webpage browsing
  • Power saving mode ensures extended battery life


  • Some users might not like the vertical orientation of this mouse
  • It may take some time to get used to

Mouse, Dark Silver

Connectivity technologyUSB
Model Name910-000806
Motion Detection TechnologyOptical

Logitech Trackman Marble mouse emphasizes the ergonomic shape and is easy to use. With its large and easy-to-reach buttons, your productivity and efficiency are guaranteed. When surfing the web or doing document editing, it is essential that the mouse can do accurate tracking across different screen surfaces.

This wired mouse runs on a Logitech 2.4 GHz wireless technology, giving you a maximum of 10 meters (33 feet) range away from its receiver without losing connection.

This ergonomic mouse also has built-in Macros for Logitech’s free control center software that lets you customize button actions, cursor speed, scrolling speed using presets or assign up to 7 actions per profile.

Product Highlights:

  • This wired mouse is compatible with Windows XP, Windows Vista, Windows 7, and Windows 8.
  • You have the option of using it left-handed or right-handed.

Final Verdict:

The Logitech Trackman Marble is the best Trackball Mouse that allows you to work without straining your wrist. The buttons are easy to press, and it runs smoothly. It’s an excellent product for anyone who spends a lot of time working on the computer, but it can also be used to play games.


  • Ambidextrous trackball design
  • Scroll wheel with tactile feedback
  • 4 customizable buttons
  • Better than Logitech MX vertical mouse


  • Lacks a few advanced features
  • Quite heavy for a trackball

ECHTPower Rechargeable Ergonomic Mouse

Connectivity TechnologyWireless
Recommended Uses For ProductOffice
Compatible DevicesLaptop, Personal Computer
Motion Detection TechnologyOptical

ECHTPower Rechargeable Ergonomic Vertical Mouse can reduce wrist pain and make your hand more comfortable. This vertical mouse is dedicated to improving and reducing hand fatigue.

It can keep the wrist and forearm in a healthy posture, reduce muscle strain, and effectively improve the wrist pain caused by using the mouse for a long time. It can be used continuously for up to 120 hours on a single charge.

The 3-level adjustable DPI can meet all your daily needs, which is suitable for office, entertainment, games, and so on. The mouse supports various devices with a USB interface (such as PC, laptop, mac, and other devices). There is a Nano USB receiver at the bottom of the mouse, so there is no need to install any drivers, just plug and play.

Product Highlights:

  • White LED battery indicator light blinks when charging and turns to solid blue light when fully charged.
  • The wireless receiver can be stored in the battery compartment for easy storage and transportation.

Final Verdict:

The ECHT Power Vertical Ergonomic Mouse is perfect for anyone who spends hours in front of a computer and has trouble using other various traditional mice due to wrist pain.

The ergonomic design keeps the wrist and forearm in a healthy posture, reducing muscle strain. Plug and Play technology allows it to connect easily to any device, making it a perfect choice.


  • Prevents wrist and forearm pain
  • Long battery life
  • Plug and play, no drivers needed
  • Wide-ranging compatibility


  • No Bluetooth
  • It doesn’t work on some surfaces

ASOI DOOMIER 2.4G Wireless Vertical Ergonomic Optical Mouse

Connectivity TechnologyUSB
Recommended Uses For ProductOffice, Gaming
Compatible DevicesWindows 2000 Windows XP Windows Vista, Windows 7, Windows 8, Windows 10 Linux , Android
Model NameBTS-911

Asoi Doomier Ergonomic Wireless Vertical Mouse comes with advanced ergonomics that reduce wrist pain and better performance. The detachable palm rest makes it comfortable for your hand.

It also comes up with 3DPI adjustable levels, 800/1200/1600, which help you play games, work on graphics, etc. It offers a stable connection with less noise of click makes it perfect.

Its 6 buttons and 15g of weight also add power to the performance you can expect from the best mouse. It is compatible with Windows 2000, XP, Vista, 7/8/10, and Linux. The USB receiver at the bottom acts as a charging port, so there is no need for a charger or Bluetooth pairing device.

Moreover, the power-saving mode can save your battery and avoid interference with other wireless devices.

Product Highlights:

  • The receiver is attached to the bottom of the mouse and battery storage position.
  • It contains two batteries, so no worries about battery life.

Final Verdict:

You can feel a real difference in how your hand feels after using Asoi Doomier Ergonomic best ergonomic mouse for wrist pain. It’s very easy to use, fits comfortably in hand, and makes less noise than other mice. You will absolutely love the adjustable DPI button; you can tailor it exactly to what you’re doing.


  • Comfortable mouse sensitivity
  • Power saving mode after 8 minutes
  • No need for additional wires
  • Cheap price for a great product


  • Not for large hands.
  • There is no option to change the angle of the thumb rest

BKLNOG Wireless Vertical Ergonomic Mouse with Wrist Support Pad

Connectivity TechnologyUSB
Compatible DevicesPersonal Computer
Model NameBE701
Motion Detection TechnologyOptical

The Bklnog’s new-gen vertical mouse comes with an ergonomically sculpted shape that keeps your hand in the least stressed handshake position, significantly reducing the wrist and forearm strains compared to using a traditional mouse which is especially helpful for CTS and RSI sufferers.

Its curved surface design provides exclusive spots for every finger movement, and its rubberized coating ensures better gripping and control of cursor movements.

It is assembled with a 2.4Ghz wireless optical sensor with the most common 800, 1200, and 1600 DPI levels and a hibernation system when the mouse is not in use, ensuring long battery life. It also comes with an optional wrist rest pad for ultimate comfort, which you can switch to anytime if you want to use the mouse more flexibly.

Product Highlights:

  • A 2.4GHz wireless optical sensor ensures high-performance tracking.
  • The hibernation system prevents the mouse from draining power when not in use.

Final Verdict:

The best part of all is that the BKLNOG vertical mouse is very easy to use, and an 18-month warranty backs it. So you can feel safe buying this product. With its awesome features, it will be no wonder if this vertical ergonomic mouse becomes a big hit!


  • Exclusive spots for finger pain
  • Detachable wrist rest mouse pad included
  • High-performance tracing
  • Ensure easy hand movement
  • Guaranteed Satisfaction


  • Requires AAA batteries
  • Some people may not like the shape

LEKVEY Rechargeable Ergonomic Mouse, Vertical Wireless Mouse

Connectivity TechnologyWireless,USB
Compatible DevicesPC
Motion Detection TechnologyOptical

Lekvey Vertical Wireless Mouse contains a scientific ergonomic design to keep the wrist and forearm in a true 45-degree “handshake” position to prevent wrist strain from prolonged use.

This mouse has rechargeable batteries, so you never have to buy batteries again! Also, it has very convenient buttons, especially “back” and “forward,” which provide convenience when web browsing.

It has 800/1200/1600DPI, which is adjustable to any situation. This mouse is widely compatible with Windows 2000 / XP / Vista 7, 8, 10, and other systems like Linux, even Mac OS. The clicking noise is quite less than the normal vertical mouse you may have used before. Moreover, you can replace or refund it with its 24-month product warranty.

Product Highlights:

  • It comes with a built-in rechargeable battery; no need to buy batteries.
  • Multifunction and convenient due to Page Back and Page Forward buttons.

Final Verdict:

The LEKVEY Vertical Wireless Mouse is a classic example of an ergonomic mouse that can help you get rid of wrist pain. The advanced ergonomic design provides an exceptional work experience that will make you feel relaxed and comfortable when operating the mouse.


  • Ergonomic design, easy to use
  • Rechargeable battery with a stable signal
  • Suitable for the majority of daily work and play situations.
  • High sensitivity that can be adjusted on demand


  • The mouse has a larger footprint than a standard mouse
  • Some users may take time to adjust to the new design

IClever Ergonomic Mouse – Wireless Vertical Mouse

Connectivity TechnologyWireless,USB
Compatible DevicesLaptop, Personal Computer
Motion Detection TechnologyOptical
Number of Buttons6

iClever Ergonomic mouse can help prevent potential injury or strain on your hand/wrist during a long time of use. It’s comfortable to hold, the premium side ridges give you a firm grip of the mouse, plus there is also an added rubber support at the bottom that prevents the wrist from moving up and down, which can cause pain.

This wireless vertical mouse with adjustable DPI saves you from the trouble of going through different sensitivity modes whenever you need higher precision.

You can even switch between vertical or horizontal orientation if it’s more convenient for you. Moreover, 5 slide pads bulge out from the bottom to ensure you can move the wireless vertical mouse smoothly without any cursor shaking, and every of your movement will be tracked precisely.

Product Highlights:

  • The 1600 dpi sensor provides accuracy and fluency without jittering.
  • The ambient lighting on the wireless vertical mouse is adjustable for a personalized style.

Final Verdict:

All in all, the iClever ergonomic mouse is an excellent option for anyone having to use the computer for long periods. It provides a high level of comfort, ease of use, and precision. With its user-friendly design, it will be the perfect pick for your work or study.


  • Backward/Forward Web Browsing Button
  • Great price for the money
  • Whisper Quiet Click for Comfortable Experience
  • Adjustable Brightness for Personalized Style


  • The wireless range is too short
  • Only One Charging Port

Considerations For Buying The Best Ergonomic Mouse:

The following are considerations for purchasing the best ergonomic mouse to reduce wrist pain. Let’s give it a quick read!

Design & Type:

Make sure the type of mouse you are buying suits your specific requirements. For instance, if you have an office job, then you need a mouse for wrist pain, but if your work involves more physical activity, then you might want to consider a trackball mouse or wireless mice. There are also ergonomic mice specifically designed for gamers.

Additional Features:

Choose a mouse with a good sensor and adjustable settings if you work on computers of different speeds or use old equipment. You can also focus on a vertical ergonomic design to reduce the pressure on your wrist or customizable buttons that can be programmed for specific functions in different applications.

Battery Life:

Some computer mice have batteries that need to be charged, but others don’t use batteries at all. Instead, they use a cable or RF technology. So, it’s up to your choice.

Scroll Wheel:

The scroll wheel is located between the left-click and right-click buttons that allow users to quickly navigate through documents or web pages.

Power Saving Mode:

If you don’t intend to use your mouse for an extended period of time, press the power saving button so that you don’t experience any inconvenience when using it next time.

DPI Switch:

If you prefer to buy a gaming mouse, go for a high dpi mouse because it will help you aim better. The dpi value stands for dots per inch and basically tells us how fast a mouse can track a movement.

Cursor Speed:

The way a normal mouse gains control over cursor movement also matters. Mice have distinct cursor speeds, and if you feel that your current mouse isn’t good enough to move the cursor in the direction you want, then purchase one with a better cursor speed.

Mouse Sensitivity:

This feature is found in gaming mice and wireless computer mice only. It lets you set the sensitivity of movement for your pointer, which is an advantage when playing games that require you to move very quickly.

Bottom Line

Ergonomic mice are a good investment because they can help reduce wrist pain to a large extent. These mice use the natural contours of the hand to provide comfortable support in your hands.

Out of all the choices available, the Perixx PERIMICE-713 Wireless Ergonomic Vertical Mouse is your best choice because it offers excellent value for money and has numerous features that enhance its usability. Otherwise, you can go for any of the mentioned options.

Frequently Asked Questions

How Do I Stop My Wrist From Hurting When I Use a Mouse?

One of the most common causes of wrist pain when using a mouse is improper positioning. The best way to avoid this is to use an ergonomic mouse that has adjustable grips and buttons in the correct locations for your hands.

Do Vertical Mice Help Wrist Pain?

Vertical mice are a popular ergonomic solution that has been shown to reduce strain on the wrist because they take the angle of your hand out of the equation. There are several different vertical mouse models, so it’s a good idea to do some research before deciding which one is right for you.

Are Ergonomic Mice Good For Carpal Tunnel?

As the name suggests, ergonomic mice are designed to reduce stress and discomfort, especially on the wrist. This is one of the factors that make them suitable for carpal tunnel syndrome and repetitive strain injury. The best ergonomic mice for such issues are those that support your wrist and align with the natural shape of your hand.

Do You Need Wrist Support With An Ergonomic Mouse?

Wrist support is beneficial for reducing wrist pain when using an ergonomic mouse. Mouse wrist rests are available to provide extra comfort and relieve some pressure on your wrists while working.

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Chris Slambery
By Chris Slambery

Chris Slambery is the founder of Gamingerra, a website devoted to technology and gaming. He's been passionate about both subjects since he was a child, and has been working in tech journalism for over a decade. When Chris isn't writing or gaming, he enjoys spending time with his wife and two young children. Chris loves keeping up to date with the latest tech news and he wants to share that information with as many people as possible. He's always been fascinated by the latest technologies and loves sharing his knowledge with others.

Gaming Erra is reader-supported. When you buy through links on our site, we may earn an affiliate commission.

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